What are the roles of abnormal metabolism and inflammation in mood disorders?

Inflammation and abnormal metabolism are observed in major depressive and bipolar disorders, said Professor Roger McIntyre of the University of Toronto, in a keynote plenary presentation for the ISBD 2020 virtual conference. The abnormalities result from both genetic and epigenetic factors and have been shown to impact both cognition and rewarding domains in the brain — which are both implicated in the pathophysiology of mood disorders.


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Our correspondent’s highlights from the symposium are meant as a fair representation of the scientific content presented. The views and opinions expressed on this page do not necessarily reflect those of Lundbeck.


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